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KMID : 1101320130450020073
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Korean Journal of Clinical Laboratory Science
2013 Volume.45 No. 2 p.73 ~ p.76
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Polysomnographic Results before and after Uvulopalatopharyngoplasty
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Kim Cheon-Sik
Kim Dae-Sik
Lee Yong-Seok
Cho Cheon-Ung
Pae Sang-Ho
Kim Won-Tae
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Abstract
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Uvulopalatopharyngoplasty (UPPP) is one possibility for the treatment of Obstructive Sleep Apnea (OSA). The aim of this study was study the analysis of polysomnography of pre-UPPP and post-UPPP. All patients were evaluated by means of a physical examination, the epworth sleepiness scale (ESS), the beck depression inventory (BDI) and the nocturnal polysomnography (PSG) before surgery, and 6∼12 months after surgery. A total of 15 patients were investigated. All underwent UPPP. The patients were between 26 and 62 years old (mean±SD; 39.7±10.9) with a lean body mass index (BMI) of mean±SD; 26.2±3.0 kg/m2. The comparison of sleep questionnaires showed that after UPPP, the patients had a significantly lower BMI (26.2±3.0 kg/m2 vs 26.0±3.4 kg/m2, p =0.241), ESS (10.0±5.4 vs 6.9±3.2, p =0.022), BDI (9.2±8.2 vs 4.2±4.3, p =0.343) and higher blood pressure (127.5±12.1 vs 123.7±12.0, p =0.272) compared to before UPPP. The comparison of sleep parameters showed that after UPPP, patients had a significantly lower stage N1 (108.8±53.1 vs 82.2±48.9, p =0.016), lower sleep latency (4.9±4.4 vs 2.0±1.7, p =0.083), a lower total arousal number (210.6±90.3 vs 147.1±87.3, p =0.019), lower oxygen desaturation index (ODI) (30.2±20.9 vs 10.2±15.1, p =0.006), lower apnea-hypopnea index (AHI) (31.6±22.4 vs 10.9±15.4, p =0.005), and a lower respiratory disturbance index (RDI) (37.4±21.3 vs 18.5±16.5, p =0.008) compared to after UPPP. The comparison of sleep parameters showed that after UPPP, patients had a significantly higher stage N2 (154.0±39.9 vs 180.5±49.5, p =0.017), higher REM (58.5±29.7 vs 72.6±34.0, p =0.249), higher meanSaO2 (94.3±2.0 vs 95.9±0.9, p =0.043), and higher minSaO2 (79.3±8.5 vs 83.1±7.9, p =0.116) than before UPPP. After UPPP, 6 patients were cured, 2 showed marked improvement, and 7 did not improve. After surgery, the success of the treatment was at 53%. The subjective patient satisfaction was higher than before the surgery.
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KEYWORD
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Uvulopalatopharyngoplasty, Obstructive sleep apnea, Polysomnography
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